HIV Target gene Detail Information

> TSC22D3 Gene Search Result

Gene Information

Gene Name	TSC22D3
Gene ID	1831
Gene Full Name	TSC22 domain family member 3
Gene Alias	DIP; GILZ; DSIPI; TSC-22R
Transcripts	ENSG00000157514
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Golgi apparatus;Nuclear speckles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q99576
HGNC ID	HGNC:3051
VEGA ID	OTTHUMG00000022168
OMIM ID	300506
String ID	9606.ENSP00000361458
PharmGKB ID	PA27504

Target gene [TSC22D3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000746	chrX	79	106	109	294	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TSC22D3 expression and immune infiltrating cell level correlation result in HIV+ samples
TSC22D3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TSC22D3 expression and immune infiltrating cell level correlation result in HIV+ samples
TSC22D3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).