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HBV Target gene Detail Information

> TRRAP Gene Search Result


Gene Information
Gene Name TRRAP
Gene ID 8295
Gene Full Name transformation/transcription domain associated protein
Gene Alias Tra1; TR-AP; PAF400; STAF40; PAF350/400
Transcripts ENSG00000196367
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Golgi apparatus;
HPA Protein Class Info Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9Y4A5
HGNC ID HGNC:12347
VEGA ID OTTHUMG00000150403
OMIM ID 603015
String ID 9606.ENSP00000352925
PharmGKB ID PA37020
Target gene [TRRAP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004662 chr7 25 18 30 73 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TRRAP expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TRRAP expression: Low -> High
Lollipop of TRRAP expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TRRAP expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TRRAP expression and immune infiltrating cell level correlation result in HBV+ samples
TRRAP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).