HTLV1 Target gene Detail Information

> TRPV1 Gene Search Result

Gene Information

Gene Name	TRPV1
Gene ID	7442
Gene Full Name	transient receptor potential cation channel subfamily V member 1
Gene Alias	VR1
Transcripts	ENSG00000196689
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	Q8NER1
HGNC ID	HGNC:12716
VEGA ID	OTTHUMG00000177649
OMIM ID	602076
Drugbank ID	BE0001023
PharmGKB ID	PA37329

Target gene [TRPV1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009780	chr17	32	2	1	35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TRPV1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRPV1 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of TRPV1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRPV1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of TRPV1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRPV1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).