HIV Target gene Detail Information

> TRPM8 Gene Search Result

Gene Information

Gene Name	TRPM8
Gene ID	79054
Gene Full Name	transient receptor potential cation channel subfamily M member 8
Gene Alias	TRPP8; LTRPC6; trp-p8; LTrpC-6
Transcripts	ENSG00000144481
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels
Uniport_ID	Q7Z2W7
HGNC ID	HGNC:17961
VEGA ID	OTTHUMG00000059129
OMIM ID	606678
String ID	9606.ENSP00000323926
Drugbank ID	BE0001186
PharmGKB ID	PA38270

Target gene [TRPM8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4012600	chr2	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TRPM8 expression and immune infiltrating cell level correlation result in HIV+ samples
TRPM8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).