HIV Target gene Detail Information

> TRPM7 Gene Search Result

Gene Information

Gene Name	TRPM7
Gene ID	54822
Gene Full Name	transient receptor potential cation channel subfamily M member 7
Gene Alias	CHAK; CHAK1; ALSPDC; LTRPC7; LTrpC-7; TRP-PLIK
Transcripts	ENSG00000092439
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Cytosol;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	Q96QT4
HGNC ID	HGNC:17994
VEGA ID	OTTHUMG00000172449
OMIM ID	605692
String ID	9606.ENSP00000320239
Drugbank ID	BE0004624
PharmGKB ID	PA38273

Target gene [TRPM7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006818	chr15	22			22	View
4011020	chr15	3	4		7	View
4011707	chr15	2	4		6	View
4012894	chr15	3	1		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TRPM7 expression and immune infiltrating cell level correlation result in HIV+ samples
TRPM7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TRPM7 expression and immune infiltrating cell level correlation result in HIV+ samples
TRPM7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).