HBV Target gene Detail Information

> TRIP13 Gene Search Result

Gene Information

Gene Name	TRIP13
Gene ID	9319
Gene Full Name	thyroid hormone receptor interactor 13
Gene Alias	MVA3; 16E1BP
Transcripts	ENSG00000071539
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q15645
HGNC ID	HGNC:12307
VEGA ID	OTTHUMG00000090349
OMIM ID	604507
String ID	9606.ENSP00000166345
PharmGKB ID	PA36986

Target gene [TRIP13] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1000437	chr5	1904	312	105	2321	View
1001110	chr5	600	407	45	1052	View
1402551	chr5	600	407	45	1052	View
1403479	chr5	1904	312	105	2321	View
1404258	chr5	27	692	581	1300	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of TRIP13 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TRIP13 expression: Low -> High
Lollipop of TRIP13 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of TRIP13 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TRIP13 expression and immune infiltrating cell level correlation result in HBV+ samples
TRIP13 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).