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HBV Target gene Detail Information

> TRIP12 Gene Search Result


Gene Information
Gene Name TRIP12
Gene ID 9320
Gene Full Name thyroid hormone receptor interactor 12
Gene Alias ULF; MRD49; TRIP-12
Transcripts ENSG00000153827
Virus HBV
Gene Type protein coding
HPA Location Info Nuclear speckles;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q14669
HGNC ID HGNC:12306
VEGA ID OTTHUMG00000153623
OMIM ID 604506
String ID 9606.ENSP00000373696
PharmGKB ID PA36985
Target gene [TRIP12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006634 chr2 34 2 36 View
1007726 chr2 25 25 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TRIP12 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TRIP12 expression: Low -> High
Lollipop of TRIP12 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TRIP12 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TRIP12 expression and immune infiltrating cell level correlation result in HBV+ samples
TRIP12 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).