HIV Target gene Detail Information

> TRIOBP Gene Search Result

Gene Information

Gene Name	TRIOBP
Gene ID	11078
Gene Full Name	TRIO and F-actin binding protein
Gene Alias	TARA; TAP68; DFNB28; dJ37E16.4; HRIHFB2122
Transcripts	ENSG00000100106
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9H2D6
HGNC ID	HGNC:17009
VEGA ID	OTTHUMG00000150657
OMIM ID	609761
String ID	9606.ENSP00000384312
PharmGKB ID	PA142670699

Target gene [TRIOBP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006351	chr22	21	4		25	View
4007641	chr22	18			18	View
4010590	chr22	7	1		8	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TRIOBP expression and immune infiltrating cell level correlation result in HIV+ samples
TRIOBP expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TRIOBP expression and immune infiltrating cell level correlation result in HIV+ samples
TRIOBP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).