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HPV Target gene Detail Information

> TRIM72 Gene Search Result


Gene Information
Gene Name TRIM72
Gene ID 493829
Gene Full Name tripartite motif containing 72
Gene Alias MG53
Transcripts ENSG00000177238
Virus HPV
Gene Type protein coding
HPA Location Info Vesicles;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transporters
Uniport_ID Q6ZMU5
HGNC ID HGNC:32671
VEGA ID OTTHUMG00000176754
OMIM ID 613288
String ID 9606.ENSP00000312675
PharmGKB ID PA144596247
Target gene [TRIM72] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403098 chr16 10 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of TRIM72 expression and immune infiltrating cell level correlation result in HPV+ samples
TRIM72 expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of TRIM72 expression and immune infiltrating cell level correlation result in HPV+ samples
TRIM72 expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of TRIM72 expression and immune infiltrating cell level correlation result in HPV+ samples
TRIM72 expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of TRIM72 expression and immune infiltrating cell level correlation result in HPV+ samples
TRIM72 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of TRIM72 expression and immune infiltrating cell level correlation result in HPV+ samples
TRIM72 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of TRIM72 expression and immune infiltrating cell level correlation result in HPV+ samples
TRIM72 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).