HTLV1 Target gene Detail Information

> TRIM61 Gene Search Result


Gene Information
Gene Name TRIM61
Gene ID 391712
Gene Full Name tripartite motif containing 61
Gene Alias RNF35
Transcripts ENSG00000183439
Virus HTLV1
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;Nucleoli fibrillar center;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q5EBN2
HGNC ID HGNC:24339
VEGA ID OTTHUMG00000161266
String ID 9606.ENSP00000332288
PharmGKB ID PA134868214
Target gene [TRIM61] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6022925 chr4 2 2 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of TRIM61 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM61 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of TRIM61 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM61 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of TRIM61 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM61 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).