HTLV1 Target gene Detail Information

> TRIM50 Gene Search Result

Gene Information

Gene Name	TRIM50
Gene ID	135892
Gene Full Name	tripartite motif containing 50
Gene Alias	TRIM50A
Transcripts	ENSG00000146755
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q86XT4
HGNC ID	HGNC:19017
VEGA ID	OTTHUMG00000156805
OMIM ID	612548
String ID	9606.ENSP00000327994
PharmGKB ID	PA38778

Target gene [TRIM50] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6023334	chr7	2	1	1	4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TRIM50 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM50 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of TRIM50 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM50 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).