HTLV1 Target gene Detail Information

> TRIM40 Gene Search Result

Gene Information

Gene Name	TRIM40
Gene ID	135644
Gene Full Name	tripartite motif containing 40
Gene Alias	RNF35
Transcripts	ENSG00000224496
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6P9F5
HGNC ID	HGNC:18736
VEGA ID	OTTHUMG00000004883
OMIM ID	616976
String ID	9606.ENSP00000379826
PharmGKB ID	PA38663

Target gene [TRIM40] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6005086	chr6	87	9		96	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TRIM40 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM40 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of TRIM40 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM40 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of TRIM40 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TRIM40 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).