HIV Target gene Detail Information

> TRIM27 Gene Search Result

Gene Information

Gene Name	TRIM27
Gene ID	5987
Gene Full Name	tripartite motif containing 27
Gene Alias	RFP; RNF76
Transcripts	ENSG00000234495
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	P14373
HGNC ID	HGNC:9975
VEGA ID	OTTHUMG00000005035
OMIM ID	602165
String ID	9606.ENSP00000366404
PharmGKB ID	PA162406956

Target gene [TRIM27] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013492	chr6	3			3	View
4015695	chr6	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TRIM27 expression and immune infiltrating cell level correlation result in HIV+ samples
TRIM27 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).