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HBV Target gene Detail Information

> TRERF1 Gene Search Result


Gene Information
Gene Name TRERF1
Gene ID 55809
Gene Full Name transcriptional regulating factor 1
Gene Alias RAPA; BCAR2; TREP132; TReP-132; HSA277276; dJ139D8.5
Transcripts ENSG00000124496
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;Nucleoli fibrillar center;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q96PN7
HGNC ID HGNC:18273
VEGA ID OTTHUMG00000014698
OMIM ID 610322
String ID 9606.ENSP00000439689
PharmGKB ID PA134923539
Target gene [TRERF1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004661 chr6 71 2 73 View
1015238 chr6 1 1 2 View
1403375 chr6 1 1 2 View
1404833 chr6 13 11 24 View
1404834 chr6 13 11 24 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TRERF1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TRERF1 expression: Low -> High
Lollipop of TRERF1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TRERF1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TRERF1 expression and immune infiltrating cell level correlation result in HBV+ samples
TRERF1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).