HBV Target gene Detail Information

> TRAPPC6A Gene Search Result


Gene Information
Gene Name TRAPPC6A
Gene ID 79090
Gene Full Name trafficking protein particle complex 6A
Gene Alias TRS33
Transcripts ENSG00000007255
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O75865
HGNC ID HGNC:23069
VEGA ID OTTHUMG00000181775
OMIM ID 610396
String ID 9606.ENSP00000006275
Drugbank ID BE0004275
PharmGKB ID PA134963625
Target gene [TRAPPC6A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007992 chr19 21 2 23 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TRAPPC6A expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TRAPPC6A expression: Low -> High
Lollipop of TRAPPC6A expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TRAPPC6A expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TRAPPC6A expression and immune infiltrating cell level correlation result in HBV+ samples
TRAPPC6A expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).