HBV Target gene Detail Information

> TRAF6 Gene Search Result


Gene Information
Gene Name TRAF6
Gene ID 7189
Gene Full Name TNF receptor associated factor 6
Gene Alias RNF85; MGC:3310
Transcripts ENSG00000175104
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;Nucleoli;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID Q9Y4K3
HGNC ID HGNC:12036
VEGA ID OTTHUMG00000166391
OMIM ID 602355
String ID 9606.ENSP00000433623
PharmGKB ID PA36713
Target gene [TRAF6] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 30404796 G1896A
PreC
View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TRAF6 expression and immune infiltrating cell level correlation result in HBV+ samples
TRAF6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).