HIV Target gene Detail Information

> TRADD Gene Search Result


Gene Information
Gene Name TRADD
Gene ID 8717
Gene Full Name TNFRSF1A associated via death domain
Gene Alias Hs.89862
Transcripts ENSG00000102871
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q15628
HGNC ID HGNC:12030
VEGA ID OTTHUMG00000137519
OMIM ID 603500
String ID 9606.ENSP00000341268
PharmGKB ID PA36707
Target gene [TRADD] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003103 chr16 66 3 69 View
4005223 chr16 34 1 35 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TRADD expression and immune infiltrating cell level correlation result in HIV+ samples
TRADD expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of TRADD expression and immune infiltrating cell level correlation result in HIV+ samples
TRADD expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).