HIV Target gene Detail Information

> TRA2B Gene Search Result


Gene Information
Gene Name TRA2B
Gene ID 6434
Gene Full Name transformer 2 beta homolog
Gene Alias SFRS10; SRFS10; TRAN2B; PPP1R156; TRA2-BETA; Htra2-beta
Transcripts ENSG00000136527
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P62995
HGNC ID HGNC:10781
VEGA ID OTTHUMG00000156641
OMIM ID 602719
String ID 9606.ENSP00000416959
PharmGKB ID PA35697
Target gene [TRA2B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001674 chr3 89 51 1 141 View
4004994 chr3 3 33 1 37 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TRA2B expression and immune infiltrating cell level correlation result in HIV+ samples
TRA2B expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).