HBV Target gene Detail Information

> TPPP Gene Search Result


Gene Information
Gene Name TPPP
Gene ID 11076
Gene Full Name tubulin polymerization promoting protein
Gene Alias p24; p25; TPPP1; TPPP/p25; p25alpha
Transcripts ENSG00000171368
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Mitochondria;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID O94811
HGNC ID HGNC:24164
VEGA ID OTTHUMG00000131011
OMIM ID 608773
String ID 9606.ENSP00000353785
PharmGKB ID PA162406809
Target gene [TPPP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002562 chr5 197 45 5 247 View
1002563 chr5 197 45 5 247 View
1002591 chr5 224 17 241 View
1003490 chr5 77 48 5 130 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TPPP expression and immune infiltrating cell level correlation result in HBV+ samples
TPPP expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).