HIV Target gene Detail Information

> TPM3 Gene Search Result

Gene Information

Gene Name	TPM3
Gene ID	7170
Gene Full Name	tropomyosin 3
Gene Alias	TM3; TM5; TRK; CFTD; NEM1; TM-5; TM30; CAPM1; TM30nm; TPM3nu; TPMsk3; hscp30; HEL-189; HEL-S-82p; OK/SW-cl.5
Transcripts	ENSG00000143549
Virus	HIV
Gene Type	protein coding
HPA Location Info	Actin filaments;Cytosol;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P06753
HGNC ID	HGNC:12012
VEGA ID	OTTHUMG00000035853
OMIM ID	191030
String ID	9606.ENSP00000357516
Drugbank ID	BE0008963
PharmGKB ID	PA36692

Target gene [TPM3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003576	chr1	23	13	22	58	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TPM3 expression and immune infiltrating cell level correlation result in HIV+ samples
TPM3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TPM3 expression and immune infiltrating cell level correlation result in HIV+ samples
TPM3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).