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HBV Target gene Detail Information

> TPCN2 Gene Search Result


Gene Information
Gene Name TPCN2
Gene ID 219931
Gene Full Name two pore segment channel 2
Gene Alias TPC2; SHEP10
Transcripts ENSG00000162341
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoli;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q8NHX9
HGNC ID HGNC:20820
VEGA ID OTTHUMG00000167898
OMIM ID 612163
String ID 9606.ENSP00000294309
PharmGKB ID PA134937857
Target gene [TPCN2] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
1001241 chr11 614 154 96 864 View
1006871 chr11 1 6 26 33 View
1008918 chr11 17 1 18 View
1401223 chr11 17 1 18 View
1401224 chr11 614 154 96 864 View
Showing 1 to 5 of 5 entries
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Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TPCN2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TPCN2 expression: Low -> High
Lollipop of TPCN2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TPCN2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TPCN2 expression and immune infiltrating cell level correlation result in HBV+ samples
TPCN2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).