HIV Target gene Detail Information

> TPCN1 Gene Search Result

Gene Information

Gene Name	TPCN1
Gene ID	53373
Gene Full Name	two pore segment channel 1
Gene Alias	TPC1
Transcripts	ENSG00000186815
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID	Q9ULQ1
HGNC ID	HGNC:18182
VEGA ID	OTTHUMG00000169625
OMIM ID	609666
String ID	9606.ENSP00000448083
PharmGKB ID	PA134922711

Target gene [TPCN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000711	chr12	301	7		308	View
4002437	chr12	32	56	6	94	View
4009809	chr12	10			10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TPCN1 expression and immune infiltrating cell level correlation result in HIV+ samples
TPCN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).