HBV Target gene Detail Information

> TP73 Gene Search Result

Gene Information

Gene Name	TP73
Gene ID	7161
Gene Full Name	tumor protein p73
Gene Alias	P73
Transcripts	ENSG00000078900
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Golgi apparatus;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene & Oncogene
Uniport_ID	O15350
HGNC ID	HGNC:12003
VEGA ID	OTTHUMG00000000610
OMIM ID	601990
String ID	9606.ENSP00000367545
Drugbank ID	BE0008919
PharmGKB ID	PA36684

Target gene [TP73] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	22962577	C1653T	C Promoter	G C	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TP73 expression and immune infiltrating cell level correlation result in HBV+ samples
TP73 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC