HTLV1 Target gene Detail Information

> TP53 Gene Search Result

Gene Information

Gene Name	TP53
Gene ID	7157
Gene Full Name	tumor protein p53
Gene Alias	P53; BCC7; LFS1; BMFS5; TRP53
Transcripts	ENSG00000141510
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters
Gene Function	Suppressor gene
Uniport_ID	P04637
HGNC ID	HGNC:11998
VEGA ID	OTTHUMG00000162125
OMIM ID	191170
String ID	9606.ENSP00000269305
Drugbank ID	BE0003380
PharmGKB ID	PA36679
FDA Approved Drug	Venetoclax

Target gene [TP53] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Detail
1	17535428	C23W	Tax	View
2	17535428	A108T	Tax	View
3	17535428	L235F	Tax	View
4	17535428	A108V	Tax	View
5	17535428	A285T	Tax	View
6	17535428	G245D	Tax	View
7	17535428	G61E	Tax	View
8	17535428	G61R	Tax	View
9	17535428	H127T	Tax	View
10	17535428	H52Y	Tax	View
11	17535428	L159F	Tax	View
12	17535428	L183F	Tax	View
13	17535428	L75F	Tax	View
14	17535428	P102L	Tax	View
15	17535428	P169L	Tax	View
16	17535428	P92L	Tax	View
17	17535428	S300F	Tax	View
18	17535428	S32F	Tax	View
19	17535428	T130I	Tax	View
20	17535428	T145I	Tax	View
21	17535428	V19M	Tax	View
22	17535428	V24E	Tax	View
23	17535428	W147L	Tax	View
24	10734308	K88A	Tax	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).