HBV Target gene Detail Information

> TP53 Gene Search Result

Gene Information

Gene Name	TP53
Gene ID	7157
Gene Full Name	tumor protein p53
Gene Alias	P53; BCC7; LFS1; BMFS5; TRP53
Transcripts	ENSG00000141510
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters
Gene Function	Suppressor gene
Uniport_ID	P04637
HGNC ID	HGNC:11998
VEGA ID	OTTHUMG00000162125
OMIM ID	191170
String ID	9606.ENSP00000269305
Drugbank ID	BE0003380
PharmGKB ID	PA36679
FDA Approved Drug	Venetoclax

Target gene [TP53] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	20962085	F141L	PreS2	G R C	View
2	26706415	A10R	X	G S C	View
3	19099581	A1762T	BCP	G C	View
4	22962577	C1653T	C Promoter	G C	View
5	31565220	I127L	X	R C	View
6	31565220	I127N	X	R C	View
7	31565220	I127S	X	R C	View
8	31565220	I127T	X	R C	View
9	31565220	K130M	X	R C	View
10	31565220	R87G	X	R C	View
11	31565220	R87W	X	R C	View
12	31565220	V131I	X	R C	View
13	21438026	A1762T	BCP	G	View
14	21438026	G1764A	BCP	G	View
15	21438026	K130M	X	G	View
16	21438026	V131I	X	G	View
17	25567052	G1764A	BCP	G	View
18	25567052	T1753A	BCP	G	View
19	29479565	A2189C	C	C	View
20	29479565	G1764A	BCP	C	View
21	17622616	P101S	X		View

Target gene [TP53] related to VISs

DVID	Chromosome	HM	TFBS	Sum of Overlapped Records	Detail
1005089	chr17	54	7	61	View
1005178	chr17	55	4	59	View
1005210	chr17	54	4	58	View
1401149	chr17	54	4	58	View
1401150	chr17	55	4	59	View
1401151	chr17	54	7	61	View

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).