HIV Target gene Detail Information

> TOX4 Gene Search Result

Gene Information

Gene Name	TOX4
Gene ID	9878
Gene Full Name	TOX high mobility group box family member 4
Gene Alias	LCP1; MIG7; C14orf92; KIAA0737
Transcripts	ENSG00000092203
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nucleoli;Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	O94842
HGNC ID	HGNC:20161
VEGA ID	OTTHUMG00000150278
OMIM ID	614032
String ID	9606.ENSP00000477868
PharmGKB ID	PA162406753

Target gene [TOX4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010486	chr13	7	2		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TOX4 expression and immune infiltrating cell level correlation result in HIV+ samples
TOX4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TOX4 expression and immune infiltrating cell level correlation result in HIV+ samples
TOX4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).