HIV Target gene Detail Information

> TOP2A Gene Search Result


Gene Information
Gene Name TOP2A
Gene ID 7153
Gene Full Name DNA topoisomerase II alpha
Gene Alias TOP2; TP2A
Transcripts ENSG00000131747
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Nucleoli;
HPA Protein Class Info Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Uniport_ID P11388
HGNC ID HGNC:11989
VEGA ID OTTHUMG00000155008
OMIM ID 126430
String ID 9606.ENSP00000411532
Drugbank ID BE0000742
PharmGKB ID PA354
Target gene [TOP2A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4004718 chr17 39 1 40 View
4005321 chr17 28 6 34 View
4007910 chr17 16 1 17 View
4008054 chr17 14 2 16 View
4008153 chr17 16 16 View
4008373 chr17 12 3 15 View
4010839 chr17 7 1 8 View
4011133 chr17 4 3 7 View
4011215 chr17 5 2 7 View
4011456 chr17 6 1 7 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).