HIV Target gene Detail Information

> TOP1 Gene Search Result


Gene Information
Gene Name TOP1
Gene ID 7150
Gene Full Name DNA topoisomerase I
Gene Alias TOPI
Transcripts ENSG00000198900
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoli fibrillar center;Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins
Uniport_ID P11387
HGNC ID HGNC:11986
VEGA ID OTTHUMG00000033057
OMIM ID 126420
String ID 9606.ENSP00000354522
Drugbank ID BE0000971
PharmGKB ID PA353
Target gene [TOP1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000213 chr20 501 83 138 722 View
4001407 chr20 91 55 23 169 View
4001651 chr20 69 56 19 144 View
4003497 chr20 16 44 60 View
4003510 chr20 39 10 11 60 View
4004064 chr20 39 11 50 View
4004065 chr20 39 11 50 View
4006695 chr20 8 11 4 23 View
4007516 chr20 10 8 1 19 View
4009625 chr20 9 2 11 View
4010377 chr20 9 9 View
4013671 chr20 1 2 3 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).