HIV Target gene Detail Information

> TOMM22 Gene Search Result

Gene Information

Gene Name	TOMM22
Gene ID	56993
Gene Full Name	translocase of outer mitochondrial membrane 22
Gene Alias	1C9-2; TOM22; MST065; MSTP065
Transcripts	ENSG00000100216
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9NS69
HGNC ID	HGNC:18002
VEGA ID	OTTHUMG00000150991
OMIM ID	607046
String ID	9606.ENSP00000216034
PharmGKB ID	PA38275

Target gene [TOMM22] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003027	chr22	67	5		72	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TOMM22 expression and immune infiltrating cell level correlation result in HIV+ samples
TOMM22 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TOMM22 expression and immune infiltrating cell level correlation result in HIV+ samples
TOMM22 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).