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HBV Target gene Detail Information

> TNRC6C Gene Search Result


Gene Information
Gene Name TNRC6C
Gene ID 57690
Gene Full Name trinucleotide repeat containing 6C
Transcripts ENSG00000078687
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q9HCJ0
HGNC ID HGNC:29318
VEGA ID OTTHUMG00000132642
OMIM ID 610741
String ID 9606.ENSP00000336783
PharmGKB ID PA134880671
Target gene [TNRC6C] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006446 chr17 16 7 15 38 View
1006934 chr17 16 4 12 32 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TNRC6C expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TNRC6C expression: Low -> High
Lollipop of TNRC6C expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TNRC6C expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TNRC6C expression and immune infiltrating cell level correlation result in HBV+ samples
TNRC6C expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).