HBV Target gene Detail Information

> TNKS Gene Search Result

Gene Information

Gene Name	TNKS
Gene ID	8658
Gene Full Name	tankyrase
Gene Alias	TIN1; ARTD5; PARPL; TINF1; TNKS1; pART5; PARP5A; PARP-5a
Transcripts	ENSG00000285372
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;Nuclear membrane;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Transporters
Uniport_ID	O95271
HGNC ID	HGNC:11941
VEGA ID	OTTHUMG00000090481
OMIM ID	603303
String ID	9606.ENSP00000311579
PharmGKB ID	PA36631

Target gene [TNKS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006950	chr8	26	6		32	View
1007474	chr8	22	5		27	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TNKS expression and immune infiltrating cell level correlation result in HBV+ samples
TNKS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).