HBV Target gene Detail Information

> TNFSF14 Gene Search Result


Gene Information
Gene Name TNFSF14
Gene ID 8740
Gene Full Name TNF superfamily member 14
Gene Alias LTg; CD258; HVEML; LIGHT
Transcripts ENSG00000125735
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID O43557
HGNC ID HGNC:11930
VEGA ID OTTHUMG00000181835
OMIM ID 604520
String ID 9606.ENSP00000469049
PharmGKB ID PA36622
Target gene [TNFSF14] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007507 chr19 22 5 27 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TNFSF14 expression and immune infiltrating cell level correlation result in HBV+ samples
TNFSF14 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).