HIV Target gene Detail Information

> TNFSF13B Gene Search Result

Gene Information

Gene Name	TNFSF13B
Gene ID	10673
Gene Full Name	TNF superfamily member 13b
Gene Alias	DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20
Transcripts	ENSG00000102524
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Focal adhesion sites;Vesicles;Predicted to be secreted;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID	Q9Y275
HGNC ID	HGNC:11929
VEGA ID	OTTHUMG00000017329
OMIM ID	603969
String ID	9606.ENSP00000365048
Drugbank ID	BE0000999
PharmGKB ID	PA434

Target gene [TNFSF13B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005630	chr13	5	16	10	31	View
4005631	chr13	5	16	10	31	View
4005632	chr13	5	16	10	31	View
4005633	chr13	5	16	10	31	View
4006145	chr13	5	12	10	27	View
4006296	chr13	5	11	10	26	View
4006441	chr13	5	10	10	25	View
4007549	chr13	5	4	10	19	View
4007768	chr13	5	3	10	18	View
4007769	chr13	5	3	10	18	View
4007998	chr13	7	1	9	17	View
4007999	chr13	7	1	9	17	View
4008276	chr13	5	1	10	16	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TNFSF13B expression and immune infiltrating cell level correlation result in HIV+ samples
TNFSF13B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TNFSF13B expression and immune infiltrating cell level correlation result in HIV+ samples
TNFSF13B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).