HBV Target gene Detail Information

> TNFRSF9 Gene Search Result

Gene Information

Gene Name	TNFRSF9
Gene ID	3604
Gene Full Name	TNF receptor superfamily member 9
Gene Alias	ILA; 4-1BB; CD137; CDw137
Transcripts	ENSG00000049249
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Nucleoli;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Predicted membrane proteins
Uniport_ID	Q07011
HGNC ID	HGNC:11924
VEGA ID	OTTHUMG00000001223
OMIM ID	602250
String ID	9606.ENSP00000478699
Drugbank ID	BE0003463
PharmGKB ID	PA36617

Target gene [TNFRSF9] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001735	chr1	420	87	4	511	View
1402231	chr1	420	87	4	511	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TNFRSF9 expression and immune infiltrating cell level correlation result in HBV+ samples
TNFRSF9 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).