HIV Target gene Detail Information

> TNFRSF4 Gene Search Result

Gene Information

Gene Name	TNFRSF4
Gene ID	7293
Gene Full Name	TNF receptor superfamily member 4
Gene Alias	OX40; ACT35; CD134; IMD16; TXGP1L
Transcripts	ENSG00000186827
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins
Uniport_ID	P43489
HGNC ID	HGNC:11918
VEGA ID	OTTHUMG00000001415
OMIM ID	600315
String ID	9606.ENSP00000368538
PharmGKB ID	PA36611

Target gene [TNFRSF4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001127	chr1	84	114	11	209	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TNFRSF4 expression and immune infiltrating cell level correlation result in HIV+ samples
TNFRSF4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TNFRSF4 expression and immune infiltrating cell level correlation result in HIV+ samples
TNFRSF4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).