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HBV Target gene Detail Information

> TNFRSF1B Gene Search Result


Gene Information
Gene Name TNFRSF1B
Gene ID 7133
Gene Full Name TNF receptor superfamily member 1B
Gene Alias p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
Transcripts ENSG00000028137
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Gene Function Oncogene
Uniport_ID P20333
HGNC ID HGNC:11917
VEGA ID OTTHUMG00000001829
OMIM ID 191191
String ID 9606.ENSP00000365435
Drugbank ID BE0000949
PharmGKB ID PA36610
Target gene [TNFRSF1B] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000640 chr1 507 528 683 1718 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TNFRSF1B expression and immune infiltrating cell level correlation result in HBV+ samples
TNFRSF1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).