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HTLV1 Target gene Detail Information

> TNFRSF1A Gene Search Result


Gene Information
Gene Name TNFRSF1A
Gene ID 7132
Gene Full Name TNF receptor superfamily member 1A
Gene Alias FPF; p55; p60; TBP1; TNF-R; TNFAR; TNFR1; p55-R; CD120a; TNFR55; TNFR60; TNF-R-I; TNF-R55
Transcripts ENSG00000067182
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins
Uniport_ID P19438
HGNC ID HGNC:11916
VEGA ID OTTHUMG00000168267
OMIM ID 191190
String ID 9606.ENSP00000162749
Drugbank ID BE0001139
PharmGKB ID PA36609
Target gene [TNFRSF1A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002547 chr12 92 111 28 231 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of TNFRSF1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
TNFRSF1A expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of TNFRSF1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
TNFRSF1A expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of TNFRSF1A expression and immune infiltrating cell level correlation result in HTLV1+ samples
TNFRSF1A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).