HPV Target gene Detail Information

> TNFRSF10C Gene Search Result

Gene Information

Gene Name	TNFRSF10C
Gene ID	8794
Gene Full Name	TNF receptor superfamily member 10c
Gene Alias	LIT; DCR1; TRID; CD263; TRAILR3; TRAIL-R3; DCR1-TNFR
Transcripts	ENSG00000173535
Virus	HPV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Predicted membrane proteins
Uniport_ID	O14798
HGNC ID	HGNC:11906
VEGA ID	OTTHUMG00000097844
OMIM ID	603613
String ID	9606.ENSP00000349324
PharmGKB ID	PA36599

Target gene [TNFRSF10C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5401684	chr8	46	10		56	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE65858 (GEO)	Head and neck squamous cell carcinoma	270	Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858
HeatMap of cell type fractions in all samples	Lollipop of TNFRSF10C expression and immune infiltrating cell level correlation result in HPV+ samples
TNFRSF10C expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of TNFRSF10C expression and immune infiltrating cell level correlation result in HPV+ samples
TNFRSF10C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).