HBV Target gene Detail Information

> TNFRSF10A Gene Search Result

Gene Information

Gene Name	TNFRSF10A
Gene ID	8797
Gene Full Name	TNF receptor superfamily member 10a
Gene Alias	DR4; APO2; CD261; TRAILR1; TRAILR-1
Transcripts	ENSG00000104689
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, CD markers, Predicted membrane proteins
Gene Function	Suppressor gene
Uniport_ID	O00220
HGNC ID	HGNC:11904
VEGA ID	OTTHUMG00000097843
OMIM ID	603611
String ID	9606.ENSP00000221132
PharmGKB ID	PA36597

Target gene [TNFRSF10A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016221	chr8		1		1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TNFRSF10A expression and immune infiltrating cell level correlation result in HBV+ samples
TNFRSF10A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).