HIV Target gene Detail Information

> TNFAIP8 Gene Search Result

Gene Information

Gene Name	TNFAIP8
Gene ID	25816
Gene Full Name	TNF alpha induced protein 8
Gene Alias	NDED; GG2-1; SCCS2; SCC-S2; MDC-3.13
Transcripts	ENSG00000145779
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O95379
HGNC ID	HGNC:17260
VEGA ID	OTTHUMG00000162949
OMIM ID	612111
String ID	9606.ENSP00000427424
PharmGKB ID	PA134957136

Target gene [TNFAIP8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003570	chr5	26	7	27	60	View
4007931	chr5	12	3	2	17	View
4010440	chr5	9			9	View
4011620	chr5	5	1		6	View
4014777	chr5		1	1	2	View
4015414	chr5	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TNFAIP8 expression and immune infiltrating cell level correlation result in HIV+ samples
TNFAIP8 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TNFAIP8 expression and immune infiltrating cell level correlation result in HIV+ samples
TNFAIP8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).