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HTLV1 Target gene Detail Information

> TMPRSS11A Gene Search Result


Gene Information
Gene Name TMPRSS11A
Gene ID 339967
Gene Full Name transmembrane serine protease 11A
Gene Alias ECRG1
Transcripts ENSG00000187054
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted membrane proteins
Gene Function Suppressor gene
Uniport_ID Q6ZMR5
HGNC ID HGNC:27954
VEGA ID OTTHUMG00000129303
OMIM ID 611704
String ID 9606.ENSP00000334611
PharmGKB ID PA142670726
Target gene [TMPRSS11A] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6023069 chr4 1 3 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of TMPRSS11A expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMPRSS11A expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of TMPRSS11A expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMPRSS11A expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of TMPRSS11A expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMPRSS11A expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).