HTLV1 Target gene Detail Information

> TMPPE Gene Search Result

Gene Information

Gene Name	TMPPE
Gene ID	643853
Gene Full Name	transmembrane protein with metallophosphoesterase domain
Transcripts	ENSG00000188167
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitochondria;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q6ZT21
HGNC ID	HGNC:33865
VEGA ID	OTTHUMG00000155779
String ID	9606.ENSP00000343398
PharmGKB ID	PA164726564

Target gene [TMPPE] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002584	chr3	226	1		227	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TMPPE expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMPPE expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).