HIV Target gene Detail Information

> TMPO Gene Search Result

Gene Information

Gene Name	TMPO
Gene ID	7112
Gene Full Name	thymopoietin
Gene Alias	TP; LAP2; CMD1T; LEMD4; PRO0868
Transcripts	ENSG00000120802
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P42166; P42167
HGNC ID	HGNC:11875
VEGA ID	OTTHUMG00000170210
OMIM ID	188380
String ID	9606.ENSP00000266732
PharmGKB ID	PA36576

Target gene [TMPO] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007082	chr12	14	7		21	View
4009492	chr12	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMPO expression and immune infiltrating cell level correlation result in HIV+ samples
TMPO expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMPO expression and immune infiltrating cell level correlation result in HIV+ samples
TMPO expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).