HBV Target gene Detail Information

> TMEM9 Gene Search Result


Gene Information
Gene Name TMEM9
Gene ID 252839
Gene Full Name transmembrane protein 9
Gene Alias DERM4; TMEM9A
Transcripts ENSG00000116857
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;Cytokinetic bridge;Microtubules;Mitotic spindle;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q9P0T7
HGNC ID HGNC:18823
VEGA ID OTTHUMG00000035831
OMIM ID 616877
String ID 9606.ENSP00000356301
PharmGKB ID PA38696
Target gene [TMEM9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004305 chr1 72 14 86 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of TMEM9 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TMEM9 expression: Low -> High
Lollipop of TMEM9 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of TMEM9 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of TMEM9 expression and immune infiltrating cell level correlation result in HBV+ samples
TMEM9 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).