HBV Target gene Detail Information

> TMEM87A Gene Search Result

Gene Information

Gene Name	TMEM87A
Gene ID	25963
Gene Full Name	transmembrane protein 87A
Transcripts	ENSG00000103978
Virus	HBV
Gene Type	protein coding
HPA Location Info	Golgi apparatus;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8NBN3
HGNC ID	HGNC:24522
VEGA ID	OTTHUMG00000172783
String ID	9606.ENSP00000374484
PharmGKB ID	PA142670739

Target gene [TMEM87A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001543	chr15	629	2	1	632	View
1005509	chr15	46	7		53	View
1005956	chr15	43	2		45	View
1006262	chr15	37	4		41	View
1006618	chr15	31	5		36	View
1015000	chr15	3			3	View
1404266	chr15	18	3		21	View
1404283	chr15	479	52	14	545	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of TMEM87A expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
TMEM87A expression: Low -> High
Lollipop of TMEM87A expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of TMEM87A expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of TMEM87A expression and immune infiltrating cell level correlation result in HBV+ samples
TMEM87A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).