HIV Target gene Detail Information

> TMEM62 Gene Search Result

Gene Information

Gene Name	TMEM62
Gene ID	80021
Gene Full Name	transmembrane protein 62
Transcripts	ENSG00000137842
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytoplasmic bodies;Nuclear bodies;Nucleoli fibrillar center;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q0P6H9
HGNC ID	HGNC:26269
VEGA ID	OTTHUMG00000176485
String ID	9606.ENSP00000260403
PharmGKB ID	PA142670775

Target gene [TMEM62] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004696	chr15	37	3		40	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMEM62 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM62 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of TMEM62 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM62 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).