HIV Target gene Detail Information

> TMEM259 Gene Search Result


Gene Information
Gene Name TMEM259
Gene ID 91304
Gene Full Name transmembrane protein 259
Gene Alias MBRL; ASBABP1; C19orf6; R32184_3; MEMBRALIN
Transcripts ENSG00000182087
Virus HIV
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;Nuclear speckles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q4ZIN3
HGNC ID HGNC:17039
VEGA ID OTTHUMG00000181905
OMIM ID 611011
String ID 9606.ENSP00000349087
PharmGKB ID PA134936083
Target gene [TMEM259] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003780 chr19 20 34 54 View
4005333 chr19 17 17 34 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of TMEM259 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM259 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).