HIV Target gene Detail Information

> TMEM245 Gene Search Result

Gene Information

Gene Name	TMEM245
Gene ID	23731
Gene Full Name	transmembrane protein 245
Gene Alias	CG2; CG-2; C9orf5
Transcripts	ENSG00000106771
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9H330
HGNC ID	HGNC:1363
VEGA ID	OTTHUMG00000020469
String ID	9606.ENSP00000363714
PharmGKB ID	PA25980

Target gene [TMEM245] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003035	chr9	58	12	1	71	View
4007013	chr9	12	9		21	View
4011807	chr9	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of TMEM245 expression and immune infiltrating cell level correlation result in HIV+ samples
TMEM245 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).