HTLV1 Target gene Detail Information

> TMEM220 Gene Search Result


Gene Information
Gene Name TMEM220
Gene ID 388335
Gene Full Name transmembrane protein 220
Transcripts ENSG00000187824
Virus HTLV1
Gene Type protein coding
HPA Location Info Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted membrane proteins
Uniport_ID Q6QAJ8
HGNC ID HGNC:33757
VEGA ID OTTHUMG00000178043
String ID 9606.ENSP00000339830
PharmGKB ID PA162406587
Target gene [TMEM220] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005073 chr17 46 49 2 97 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of TMEM220 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMEM220 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).