HTLV1 Target gene Detail Information

> TMEM218 Gene Search Result

Gene Information

Gene Name	TMEM218
Gene ID	219854
Gene Full Name	transmembrane protein 218
Transcripts	ENSG00000150433
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	A2RU14
HGNC ID	HGNC:27344
VEGA ID	OTTHUMG00000165880
OMIM ID	619285
String ID	9606.ENSP00000436596
PharmGKB ID	PA162406569

Target gene [TMEM218] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002895	chr11	24	57	120	201	View
6013063	chr11	20			20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of TMEM218 expression and immune infiltrating cell level correlation result in HTLV1+ samples
TMEM218 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).